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Tổng quan Issue: Số 33 - 2022 Bệnh mạch máu não

Lacunar Syndromes

Published: June 15, 2022
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Abstract

This review provides an overview of lacunar syndromes, the clinical manifestations of lacunar infarction caused by cerebral small vessel disease. It discusses the historical background, epidemiology, pathophysiology, risk factors, and the five classic lacunar syndromes, together with neuroimaging characteristics on computed tomography and magnetic resonance imaging. The article also summarizes current principles of acute management, secondary stroke prevention, and risk factor control to reduce recurrent stroke and improve long-term outcomes in patients with lacunar infarction.

Keywords
Lacunar syndrome Lacunar infarction Cerebral small vessel disease Ischemic stroke

References

1.
Dechambre A. Mémoire sur la curabilité du ramollissement cérébral. *Gaz Med Paris*. 1838; 6:305.
2.
Fisher C.M. Lacunes: Small, Deep Cerebral Infarcts. *Neurology*. 1965; 15:774.
3.
Gorelick P.B. The global burden of stroke: persistent and disabling. *Lancet Neurology*. 2019; 18(5):417-418.
4.
Petty G.W., Brown R.D., Whisnant J.P., Sicks J.D., O'Fallon W.M., Wiebers D.O. Ischemic stroke subtypes: a population-based study of incidence and risk factors. *Stroke*. 1999; 30(12):2513-2516.
5.
Loeb C., Gandolfo C., Croce R., Conti M. Dementia associated with lacunar infarction. *Stroke*. 1992; 23(9):1225-1229.
6.
Fisher C.M. Capsular infarcts: the underlying vascular lesions. *Archives of Neurology*. 1979; 36:65.
7.
Feekes J.A., Hsu S.W., Chaloupka J.C., Cassell M.D. Tertiary microvascular territories define lacunar infarcts in the basal ganglia. *Annals of Neurology*. 2005; 58:18.
8.
Fisher C.M. Lacunar strokes and infarcts: a review. *Neurology*. 1982; 32:871.
9.
Blevins B.L., Vinters H.V., Love S., et al. Brain arteriolosclerosis. *Acta Neuropathologica*. 2021; 141:1.
10.
Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. *Lancet Neurology*. 2010; 9:689.
11.
Caplan L.R. Intracranial branch atheromatous disease: a neglected, understudied, and underused concept. *Neurology*. 1989; 39:1246.
12.
Macdonald R.L., Kowalczuk A., Johns L. Emboli enter penetrating arteries of monkey brain in relation to their size. *Stroke*. 1995; 26:1247.
13.
Hart R.G., Foster J.W., Luther M.F., Kanter M.C. Stroke in infective endocarditis. *Stroke*. 1990; 21:695.
14.
Cacciatore A., Russo L.S. Jr. Lacunar infarction as an embolic complication of cardiac and arch angiography. *Stroke*. 1991; 22:1603.
15.
Wardlaw J.M., Sandercock P.A., Dennis M.S., Starr J. Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia? *Stroke*. 2003; 34:806.
16.
Wardlaw J.M. What causes lacunar stroke? *Journal of Neurology, Neurosurgery & Psychiatry*. 2005; 76:617.
17.
Traylor M., Persyn E., Tomppo L., et al. Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies. *Lancet Neurology*. 2021; 20:351.
18.
Chamorro A., Sacco R.L., Mohr J.P., et al. Clinical-computed tomographic correlations of lacunar infarction in the Stroke Data Bank. *Stroke*. 1991; 22:175.
19.
Hommel M., Besson G., Le Bas J.F., et al. Prospective study of lacunar infarction using magnetic resonance imaging. *Stroke*. 1990; 21:546.
20.
Koch S., McClendon M.S., Bhatia R. Imaging evolution of acute lacunar infarction: leukoariosis or lacune? *Neurology*. 2011; 77:1091.
21.
Kwok C.S., Shoamanesh A., Copley H.C., et al. Efficacy of antiplatelet therapy in secondary prevention following lacunar stroke: pooled analysis of randomized trials. *Stroke*. 2015; 46:1014.
22.
SPS3 Investigators, Benavente O.R., Hart R.G., et al. Effects of clopidogrel added to aspirin in patients with recent lacunar stroke. *New England Journal of Medicine*. 2012; 367:817.

Authors

Nguyễn Thị Hường Bệnh viện Đa khoa Quốc tế Vinmec Times City Nguyễn Thanh Bình Đại học Y Hà Nội
Lacunar Syndromes

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Section Tổng quan
Category Bệnh mạch máu não
Pages 45-51
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