Abstract
Progressive supranuclear palsy (PSP) is the most common neurodegenerative disorder among the atypical parkinsonian syndromes. The characteristic clinical features of PSP include vertical supranuclear gaze palsy, postural instability with recurrent unexplained falls, bradykinesia, and cognitive impairment. Neuropathologically, PSP is characterized by the abnormal accumulation of tau protein and is classified as a primary tauopathy.
Progressive supranuclear palsy
Atypical parkinsonism
Tau protein
Movement disorders