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Nghiên cứu lâm sàng Số phát hành: Số 51 - 2026 Đột quỵ

Outcomes of emergent carotid artery stenting for tandem occlusion in acute ischemic stroke: a single center retrospective study

Xuất bản: tháng 10 24, 2026
Lượt đọc: 9

Tóm tắt

Objectives: To describe outcomes and explore factors associated with functional recovery after emergent carotid stenting for acute ischemic stroke with tandem occlusion.
Methods: This retrospective study included 90 patients treated at Bach Mai Hospital from February 1, 2024, to January 31, 2026. Favorable outcome was a modified Rankin Scale score of 0-2 at 30 days.
Results: Successful reperfusion was achieved in 94.4%; 47.8% had favorable outcomes and 12.2% died by 30 days. Imaging-defined hemorrhagic transformation occurred in 58.9%; internal carotid and middle cerebral artery re-occlusion occurred in 8.9% and 4.4%, respectively. Among 53 patients with hemorrhagic transformation, hemorrhagic infarction was associated with higher odds of favorable outcome than parenchymal hematoma (odds ratio [OR], 6.74; 95% confidence interval [CI], 1.34-33.82; p=0.015). Procedure time ≤60 minutes was also associated with favorable outcome (OR, 2.56; 95% CI, 1.05-6.25; p=0.037).
Conclusions: Successful reperfusion was frequent, but imaging-defined hemorrhagic transformation was common. These unadjusted associations require cautious interpretation because of the small retrospective cohort and absence of a non-stenting comparator.

Từ khóa
acute ischemic stroke Tandem occlusion carotid artery stenting mechanical thrombectomy endovascular therapy

Tài liệu tham khảo

1.
Farooqui M, Zaidat OO, Hassan AE, et al. Functional and safety outcomes of carotid artery stenting and mechanical thrombectomy for large vessel occlusion ischemic stroke with tandem lesions. JAMA Netw Open. 2023;6(3):e230736. doi:10.1001/jamanetworkopen.2023.0736\
2.
Anadani M, Marnat G, Consoli A, et al; TITAN and ETIS Registry Investigators. Endovascular therapy of anterior circulation tandem occlusions: pooled analysis from the TITAN and ETIS registries. Stroke. 2021;52(10):3097-3105. doi:10.1161/STROKEAHA.120.033032\
3.
Romoli M, Molina CA, Zapata-Arriaza E, et al; CERES-TANDEM. Emergent carotid stenting for acute anterior circulation ischemic stroke with tandem lesions: the multicenter CERES-TANDEM study. Neurology. 2026;106(2):e214528. doi:10.1212/WNL.0000000000214528\
4.
Grigoryan M, Haussen DC, Hassan AE, et al. Endovascular treatment of acute ischemic stroke due to tandem occlusions: large multicenter series and systematic review. Cerebrovasc Dis. 2016;41(5-6):306-312. doi:10.1159/000444069\
5.
Pop R, Hasiu A, Mangin PH, et al. Postprocedural antiplatelet treatment after emergent carotid stenting in tandem lesions stroke: impact on stent patency beyond day 1. AJNR Am J Neuroradiol. 2021;42(5):921-925. doi:10.3174/ajnr.A6993\
6.
Wallocha M, Chapot R, Nordmeyer H, Fiehler J, Weber R, Stracke CP. Treatment methods and early neurologic improvement after endovascular treatment of tandem occlusions in acute ischemic stroke. Front Neurol. 2019;10:127. doi:10.3389/fneur.2019.00127

Tác giả

Nguyễn Thùy Anh Thư Trường Đại học Y Dược, Đại học Quốc gia Hà Nội Nguyễn Thị Bảo Liên Bệnh viện Đa khoa Xanh Pôn Trần Anh Tuấn Bệnh viện Bạch Mai; Trường Đại học Y Dược, Đại học Quốc gia Hà Nội Đỗ Khánh Hà Bệnh viện Đa khoa Quốc tế Vinmec Ocean Park 2
Outcomes of emergent carotid artery stenting for tandem occlusion in acute ischemic stroke: a single center retrospective study

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Số phát hành Số 51 - 2026
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